TY - JOUR

T1 - Predictors and moderators of outcome of psychotherapeutic interventions for mental disorders in adolescents and young adults

T2 - protocol for systematic reviews

AU - Vousoura, Eleni

AU - Gergov, Vera

AU - Tulbure, Bogdan Tudor

AU - Camilleri, Nigel

AU - Saliba, Andrea

AU - Garcia-Lopez, Luis Joaquin

AU - Podina, Ioana R.

AU - Prevendar, Tamara

AU - Löffler-Stastka, Henriette

AU - Chiarenza, Giuseppe Augusto

AU - Debbané, Martin

AU - Markovska-Simoska, Silvana

AU - Milic, Branka

AU - Torres, Sandra

AU - Ulberg, Randi

AU - Poulsen, Stig

N1 - Funding Information: The authors would like to thank prof. Dr. Pim Cuijpers, prof. Dr. Marcus Huibers, and Dr. Eirini Karyotaki for their valuable training in systematic reviews and meta-analyses. We also thank information specialists Katri Larmo and Tiina Heino from Terkko Medical Campus Library at the University of Helsinki for their help in forming the search strings for the databases. Publisher Copyright: © 2021, The Author(s).

PY - 2021/12

Y1 - 2021/12

N2 - Background: Adolescence and young adulthood is a risk period for the emergence of mental disorders. There is strong evidence that psychotherapeutic interventions are effective for most mental disorders. However, very little is known about which of the different psychotherapeutic treatment modalities are effective for whom. This large systematic review aims to address this critical gap within the literature on non-specific predictors and moderators of the outcomes of psychotherapeutic interventions among adolescents and young adults with mental disorders. Methods: The protocol is being reported in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) Statement. PubMed and PsycINFO databases will be searched for randomized controlled and quasi-experimental/naturalistic clinical trials. Risk of bias of all included studies will be assessed by the Mixed Methods Appraisal Tool. The quality of predictor and moderator variables will be also assessed. A narrative synthesis will be conducted for all included studies. Discussion: This systematic review will strengthen the evidence base on effective mental health interventions for young people, being the first to explore predictors and moderators of outcome of psychotherapeutic interventions for a wide range of mental disorders in young people. Systematic review registration: PROSPERO CRD42020166756.

AB - Background: Adolescence and young adulthood is a risk period for the emergence of mental disorders. There is strong evidence that psychotherapeutic interventions are effective for most mental disorders. However, very little is known about which of the different psychotherapeutic treatment modalities are effective for whom. This large systematic review aims to address this critical gap within the literature on non-specific predictors and moderators of the outcomes of psychotherapeutic interventions among adolescents and young adults with mental disorders. Methods: The protocol is being reported in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) Statement. PubMed and PsycINFO databases will be searched for randomized controlled and quasi-experimental/naturalistic clinical trials. Risk of bias of all included studies will be assessed by the Mixed Methods Appraisal Tool. The quality of predictor and moderator variables will be also assessed. A narrative synthesis will be conducted for all included studies. Discussion: This systematic review will strengthen the evidence base on effective mental health interventions for young people, being the first to explore predictors and moderators of outcome of psychotherapeutic interventions for a wide range of mental disorders in young people. Systematic review registration: PROSPERO CRD42020166756.

KW - Individualized treatment

KW - Mental health

KW - Moderators

KW - Predictors

KW - Psychotherapeutic interventions

KW - Young people

UR - http://www.scopus.com/inward/record.url?scp=85113871251&partnerID=8YFLogxK

U2 - 10.1186/s13643-021-01788-1

DO - 10.1186/s13643-021-01788-1

M3 - Journal article

C2 - 34462006

AN - SCOPUS:85113871251

VL - 10

JO - Systematic Reviews

JF - Systematic Reviews

SN - 2046-4053

M1 - 239

ER -